It is now obvious that direct analysis of DNA and protein could dramatically improve speed, accuracy, and sensitivity over conventional molecular diagnostic methods. However, DNA, RNA, protein, and their functional subcellular scaffolds and compartments are in the nanometer scale, the potential of single molecule analysis approach would not be fully realized without the help of nanobiotechnology. Advances in nanotechnology are providing nanofabricated devices that are small, sensitive, and inexpensive enough to facilitate direct observation, manipulation, and analysis of a single biological molecule from a single cell. This opens new opportunities and provides powerful tools in fields such as genomics, proteomics, molecular diagnostics, and high-throughput screening. Given the inherent nanoscale of receptors, pores, and other functional components of living cells, the detailed monitoring and analysis of these components will be made possible by the development of a new class of nanoscale probes. The most important area of application will be in point-of-care diagnostics. Important indications will include cancer diagnosis and detection of infectious disease agents, particularly in bioterror attacks. Future trends in diagnostics will continue in the miniaturization of biochip technology to nano range. There is also a trend
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.