In summary, PCR-based DNA fingerprinting techniques are becoming increasingly used for a wide range of organisms, and AFLP analysis has considerable advantages for certain applications. The method is robust, relatively easy to perform, sufficiently reproducible to provide the basis for reliable intralaboratory and inter-laboratory studies, and can be easily modified (tuned) to provide the desired level of discrimination. AFLP markers have a high multiplex ratio (the number of different genetic loci that may be simultaneously analyzed per experiment), which is of considerable advantage because this allows analysis of, at least in part, the entire genome rather than single locations.[35,36] AFLP has been successfully applied to fingerprint DNA material from a very wide variety of biological sample including plants, animals, viruses, and both eukaryotic and prokaryotic

microorganisms.[1,7,37,38- Applications have been particularly successful in the areas of analysis of plant genomes and those from pathogenic bacteria for public health microbiology and molecular epidemiology. Until very high throughput multiple-sequence analysis of whole genomes becomes technically feasible on a wide and rapid scale, AFLP should be seriously considered as the method of choice to investigate genome polymorphisms.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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