Cyp3a5

<1

Drugs

CYP3A5*3

Not shown

aThe estimated fraction of responsibility for drug metabolism in phase 1 reactions.

bA description of the alleles is found on the human CYP allele nomenclature committee home page: http://www.imm.ki.se/CYPalleles/. cThe significance of the polymorphism is based on the number of reports showing impact of the P450 polymorphism on the pharmacokinetics of drugs being substrates for the enzyme in question. The number of + illustrates the relative importance between the different forms of P450. Source: Ref. [2].

aThe estimated fraction of responsibility for drug metabolism in phase 1 reactions.

bA description of the alleles is found on the human CYP allele nomenclature committee home page: http://www.imm.ki.se/CYPalleles/. cThe significance of the polymorphism is based on the number of reports showing impact of the P450 polymorphism on the pharmacokinetics of drugs being substrates for the enzyme in question. The number of + illustrates the relative importance between the different forms of P450. Source: Ref. [2].

Table 2 Examples of clinical impact of cytochrome P450 pharmacogenetics

Disease

Depression

Psychosis Ulcer Cancer CV

Pain

Epilepsia

Enzyme

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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