Resistance to conventional antimalarials is escalating, and novel strategies to monitor for resistance are needed. There are no simple bedside methods for assessing antimalarial drug susceptibility. Therapeutic response to antimalarials can be assessed in vivo by using the World Health Organization (WHO) treatment protocols, as well as in vitro by measuring the parasite's sensitivity by inhibition of growth or maturation of blood stages. Both of these strategies have a number of limitations.1-12-1 More recently, a number of studies have begun to elucidate the genetic basis of drug resistance. This information has been translated into molecular assays to characterize malaria isolates for genetic markers of drug resistance. These studies have now been extended, suggesting that these biomarkers can be useful in predicting treatment failures and that they can be used to detect and track global patterns of drug-resistant malaria.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.