Diagnosis

Besides the picture described above, diagnosis of both p-thalassemia major and p-thalassemia intermedia is based on the following hematological features:

1. Typical peripheral blood smear showing microcytosis, hypochromia, anisocytosis, poikilocytosis, and nucleated red blood cells.

2. Hb pattern (by cellulose acetate electrophoresis or HPLC), characterized by HbF, and trace of HbA2 (p°-thalassemia) or 10-30% HbA, 70-90 HbF, and trace of HbA2 (p+-thalassemia).

3. Complete absence (^"-thalassemia) or extreme reduction (p+-thalassemia) of p-chains by in vitro synthesis of radioactive-labeled globin chains.[2,3]

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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