Clinical history in the presence of laboratory prolongation of PT and PTT usually suggests FX deficiency. Specific diagnosis relies on the quantification of FX activity and antigen levels and on the levels of other coagulation factors. Concomitant disease may mimic congenital FX deficiency. Liver disease and vitamin K deficiency can be responsible for acquired FX deficiency, but they more commonly determine abnormalities of other VKD clotting factors. Acquired FX inhibitors have been reported and can be suspected when sample plasma added to normal plasma causes prolongation of PT and PTT. Amyloidosis has been shown to determine FX deficiency by amyloid protein binding to circulating FX.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.