Disinfection And Treatment

Person-to-person transmission of legionellosis has not been published. Therefore, prevention of Legionella infections refers to the elimination of the pathogen from water supplies. Several methods for controlling the growth of legionellae in drinking water (superheating, ultraviolet light irradiation, ozonation, metal ionization, chlorination) have been described.[24]

With respect to human infection, prompt diagnosis and treatment appear to be critical, because delay in starting an appropriate therapy has been associated with increased mortality. Legionellae are intracellular pathogens, and thus antibiotics that achieve high intracellular concentration are more efficacious than those with poor intracellular penetration. Historically, erythromycin has been the drug of choice. Macrolides, quinolones, rifampicin, trimethor-pim-sulfamethoxazole, and tetracyclines are effective agents in vitro. According to in vitro studies, the newer macrolides, especially clarithromycin and azithromycin, and quinolones are the drugs of choice for Legionella infections.[5,8]

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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