Epidemiology

In many industrialized countries, the number of syphilis infections has declined significantly. In the United States, the rate of infection so far in 2003 is fewer than four cases per 100,000 population; however, the number of cases is expected to fluctuate, and syphilis remains a significant health problem in many major U.S. cities. Meanwhile, the disease remains endemic in many other parts of the world. The World Health Organization in 1999 reported 12 million new cases worldwide, with some regions showing a significant increase in prevalence.1-4-1 For example, the Russian Federation experienced a 26-fold increase of congenital syphilis from 1991 to 1999.[5] With current high rates of international travel, STD infections in one endemic region may easily become a significant problem in other parts of the world.[6] Concurrent HIV infection also alters the natural history of syphilis. Rapid progression from primary syphilis to neurosyphilis has been observed in many coinfected individuals. While no penicillin-resistant strains of T. pallidum have been reported, erythromycin-resistant T. pallidum has been described and results from a single base pair mutation in both copies of the 23S rRNA gene.[7]

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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