An interesting approach that will have a high impact is to combine FISH with morphologic or immunohistochemi-cal assays to examine the cytogenetic pattern of specific cell populations. This is possible because FISH does not require the destruction of the cell structure and tissue morphology. In the future, even more important than I-FISH will be a technique called fluorescence immuno-phenotyping and interphase cytogenetics as a tool for investigation of neoplasms (FICTION). This method allows the detection of genetic aberrations in immuno-logically characterized cell populations, even if they present a minority in the tissue studied. Using this approach, the sensitivity of interphase FISH can be even enhanced because only certain cell subpopulations are
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.