Genetics

The genes for a, p, and g subunits have been cloned.[28] The genes for both muscle and liver a subunit have been mapped to X chromosome (aL at Xp22.2 and aM at Xq12) and the one for p subunit to chromosome 16q12-q13. A number of mutations for different forms of phosphorylase kinase deficiency have been character-ized.[26-28] The gene for muscle g subunit (gM, PHKG1) has been localized to chromosome 7p12.[29] No mutations in this gene have been reported so far. Gene for liver/ testis-specific g subunit (gTL, PHKG2) maps to chromosome 16p12.1 and many disease-causing mutations are known for this gene.[28]

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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