Huntingtons Disease

Huntington's disease (HD) is an inherited neurological disorder characterized by an intractable course of mental deterioration and progressive motor abnormalities with death usually occurring within 15-17 years. There are no treatments for HD. Recent studies have suggested that CNTF might slow the neural degeneration in HD.[13-15] Clinical trials are underway to determine the safety and tolerability of CNTF-producing cells implanted into the lateral ventricle of HD patients.[16] Although the results of this trial are not yet available, the trial is designed using a device containing as many as 106 CNTF-producing BHK cells producing 0.15-0.50 mg CNTF/day implanted into the right lateral ventricle of six patients. In this phase I study, the principal goal is to evaluate the safety and tolerability of the procedure. HD symptoms will also be analyzed using neuropsychological, motor, neurological, and neurophysiological tests and the striatal pathology monitored using MRI and PET-scan imaging.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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