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Fig. 1 Classification of hemophilia B.

Fig. 1 Classification of hemophilia B.

or chromogenic assay and the diagnosis is confirmed. In those without a previous history, the deficiency of factor IX must be distinguished from deficiencies of FVIII and XI, all of which may also give a prolonged APTT. When the diagnosis is confirmed, identification of the molecular abnormality of the factor IX gene will facilitate carrier screening in other family members.

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