Fig. 2 Spectral and DAPI image of a normal human metaphase (top left and top right, respectively), and a spectral image showing the analyzed karyogram of scc078, an oral squamous cell carcinoma cell line (bottom). The karyogram shows a multitude of unbalanced translocated chromosomes. (View this art in color at www.dekker.com.)
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A spectral karyotyping system consists of a high-quality fluorescence microscope (e.g., Leica RA) with a special filter set. A high-resolution CCD camera (1280 x 1024 pixels) and a special device for spectral analysis (SpectraCube™) sit above this. The system is completely integrated with and controlled by a highperformance Windows NT-based computer with dedicated control, imaging, and analysis software (SpectraView Software, Applied Spectral Imaging Inc., Israel) and includes printing and storage devices.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.