Introduction

Several technologies for probing genetic variation have emerged in the past 20 years, many of which incorporate in vitro enzymatic DNA amplification by the polymerase chain reaction (PCR) in its modern, Taq-polymerase-based incarnation. Among them, amplification refractory mutation system (ARMS)-PCR stands out for its speed, simplicity, versatility, and low cost. Since its concurrent inception by six separate groups working independently,[1-6] these features of ARMS-PCR have established it as arguably the single, most popular geno-typing technique. Evidence of this abounds in the scientific literature despite some confusing nomenclature issues that persist today (Table 1). The popularity of ARMS-PCR is also apparent by its continuous development over the years (Table 2). Today, ARMS-PCR embraces all formats, from single tube to array, and all conceivable applications, from SNP to universal genotyping.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

Get My Free Ebook


Post a comment