The human caliciviruses have recently been subdivided into the Norovirus and the Sapovirus genera. Norwalk agent was the first human viral enteropathogen to be described. It was designated the cause of ''Winter vomiting disease'' and named after Norwalk, Ohio, USA, in 1972. They do not have a classic calicivirus morphology on electron microscopy and were also referred to as small round structured viruses (SRSV). The sapoviruses are named after a virus found in Sapporo, Japan, in 1982. They have the classical cup-shaped depressions (calyx is Greek for a cup) in their surface when viewed by negative stain electron microscopy. The noroviruses are an important cause of vomiting with or without diarrhea and are responsible for large outbreaks of disease in the community, in hospitals, or on cruise liners. After rotavirus they are the most important etiological agents of gastroenteritis. The sapoviruses cause mild diarrheal disease predominantly in children.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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