Gross chromosonal abnormalities leading to gains and losses of (parts of) chromosomes are frequent events in the majority of cancers, especially in solid tumors. Microarray-based comparative genomic hybridization (array-CGH) is the most versatile technique currently available for detecting DNA copy number changes. We will review the array-CGH technique that, as the conventional comparative genomic hybridization (CGH), is able to detect DNA copy number changes throughout the whole genome in one single experiment, but with much higher resolution. Applications and future developments of array-CGH will also be discussed.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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