The reference standard essential for all molecular biology is direct nucleotide sequencing. This ''Gold'' standard is used for studies ranging from gene mutation screening in human disease to the sequencing of an entire genome. Sequencing protocols had been developed that used either chemicals or dideoxy nucleotides, although the former became less popular because of the use of toxic chemicals. If direct nucleotide sequencing was less expensive then there would not be the need for mutation screening techniques.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.