Introduction

The latest achievements in molecular biology and medicine and the evolution of new diagnostic microdevices are driving the implementation of nucleic acid-based technologies (NABT) in the medical laboratory and are contributing to the emerging utilization of point-of-care testing (POCT). These developments will be changing the medical laboratory and medicine in general. With the increasing recognition of new infectious diseases, the potential threat of global bioterrorism, the evolving identification of genetic markers for disease risk and drug side reactions, and new technology available, there is an increased interest in the potential applications of nucleic acid-based tests in a point-of-care setting. Several years ago nucleic acid-based technologies (NABT) seemed to move only slowly into the medical laboratory,[1] but currently several nucleic acid-based tests have already replaced traditional assays and turned into gold standard, in particular in the field of diagnostic microbiology.[2] Differentiating POCT from regular laboratory testing is somewhat artificial, but is a useful simplification from the health-care management perspective to describe testing by nonlaboratoty staff using specialized diagnostic equipment adapted for near-patient applications. Point-of-care testing has a number of names and definitions: ancillary testing, bedside testing, alternate site testing, and decentralized testing all mean POCT. Point-of-care testing includes simple self-care tests that patients can perform by themselves at home, tests that are performed in the doctor's office, and tests that are performed by personnel, e.g., in the intensive care unit, the emergency room, the ward, or in the battlefield area.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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