Widespread use of broad-spectrum antibiotics triggered the emergence of Clostridium difficile as an important bacterial pathogen associated with diarrhea and colitis in hospitalized patients. This toxigenic bacterium causes significant morbidity and mortality, and imposes a pronounced economic burden on the health system. Appropriate treatment requires efficient diagnosis, and several techniques have been developed to detect toxins produced by this microbe. However, immunodetection techniques often lack sensitivity, whereas cytotoxicity assays can only be performed in laboratories equipped with tissue culture facilities. Newer and faster methods based on rapid detection of genes encoding the toxins are providing promising simpler approaches.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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