Glycogen storage diseases (GSDs) are inherited disorders affecting glycogen metabolism. The glycogen found in GSDs is abnormal either in quantity or quality. Liver and muscle are the most common and seriously affected tissues. The liver GSDs usually present with hepatomegaly and hypoglycemia. The GSDs primarily affecting the liver are types I, III, IV, VI, and IX. The most common features of muscle GSDs are muscle cramps, exercise intolerance, fatigue, and progressive weakness. GSDs principally affecting the muscle include GSD type II (lysosomal enzyme deficiency), V, VII, and IX (phos-phorylase kinase deficiency).

The frequency of all forms of GSDs is approximately 1 in 20,000-25,000 live births. GSD types I, II, III, VI, and IX are the most common, and they account for approximately 90% of all GSDs.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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