Introduction

The Ehlers-Danlos syndrome (EDS) comprises a clinically and genetically heterogeneous group of connective tissue diseases of which the principle clinical features are skin hyperextensibility, joint hypermobility, and generalized connective tissue fragility. These clinical manifestations are present, to varying degrees, in each subtype of the condition. The latest classification of EDS, the Villefranche nosology, recognizes six subtypes for which major and minor diagnostic criteria were defined. The classic, hypermobile, and vascular type of EDS are the most common, whereas the kyphoscoliosis, arthrochalasis, and dermatosparaxis type constitute very rare conditions. Several EDS subtypes are caused by mutations in the structural genes for type I (arthrochalasis type), type III (vascular type), or type V collagen (classic type) or in genes involved in the processing of type I collagen (kyphoscoliosis and dermatosparaxis type).

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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