Introduction

Techniques for detection and quantitation of a given nucleic acid sequence can be divided into three categories: 1) approaches for target amplification including polymerase chain reaction (PCR), nucleic acid sequence-based amplification (NASBA), transcription-mediated amplification (TMA), or strand displacement amplification (SDA), 2) probe amplification systems such as ligase chain reaction (LCR), and 3) methods that do not alter the number of target molecules but dramatically increase the signal generated by nucleic acid sequences present in the original specimen. One of the signal amplification strategies involves the so-called branched DNA (bDNA) and the following article will attempt to provide a short overview of the basic principles as well as specific clinical and research applications of this technology.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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