Factor IX plays an important role in blood coagulation. Hereditary deficiency of factor IX leads to the bleeding disorder hemophilia B, which is clinically indistinguishable from the more common hemophilia A (Factor VIII deficiency). Hemophilia B is a recessively inherited X-linked disorder with a world-wide incidence of 1/30,00050,000. Advances in our knowledge of the factor IX protein and its functional activity and in the factor IX gene and the genetic defects associated with hemophilia B have led to major diagnostic and therapeutic advances in this disorder.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.