Duchenne muscular dystrophy (DMD) is a common inherited disease with a worldwide incidence of 1 in 3500 male births. DMD is a lethal disorder of childhood characterized by progressive muscle wasting. Affected individuals are wheelchair-bound by the age of 12 and succumb to cardiac or respiratory failure in their mid to late 20s.
Dystrophin, the gene defective in DMD was isolated in 1986. Since then, genetic diagnosis of DMD has been done leading to better understanding of the disease process. Based on the molecular pathogenesis of DMD, molecular therapies for DMD have been proposed.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.