M1000

The m1000 sample preparation platform (Abbott Laboratories, Abbott Park, USA) uses a magnetic particle technology for the extraction and purification of RNA and DNA. It provides a fully automated sample preparation and is capable of processing 48 samples within 2 hr for a sample volume of 1 mL. Analyte-specific reagents (ASR) may be used for the preparation of samples for hepatitis C virus analysis as well as for the extraction of human DNA for HLA typing. The robot contains liquidlevel sensing and a clot detection system. Standard primary bar-coded tubes are used.

Silva et al.[7] evaluated the performance of the m1000 instrument for the extraction of genomic human DNA from frozen blood specimens followed by HLA-DRB sequencing-based typing. Their results showed that the DNA yield was consistently high with an average concentration of 20 ng/pL (from 0.2 mL blood). The average (260:280 nm) ratio was 1.7, and the purified DNA was free of inhibitors; all DNA samples could successfully be amplified and sequenced.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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