Maintenance Regimens

Despite the success of ERT for symptomatic patients, one must ask whether dose adjustments and/or circumscribed ''drug vacations'' may be suggested in individual patients who have had up to 10 years of therapy, particularly those who have achieved near-normalization of major disease parameters. This argument is particularly cogent in light of a report that documents the continuation of the beneficial effects of enzyme on disease parameters after varying periods of withdrawal, with no deterioration among adults.[14] Drug vacations should not be considered for children.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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