Prehospital treatment with intramuscular penicillin is recommended where disease is suspected, because deterioration of the patient's condition can be rapid. Although meningococci with intermediate resistance to penicillin have been described, they have not been associated with treatment failure. In practice, before a diagnosis is established, most patients will be treated with a third-generation cephalosporin such as ceftriaxone to give broad-spectrum antibiotic cover where the causative organism is not yet identified. There are no reports of resistant meningococci for this antibiotic.

The severe nature of meningococcal disease means that good supportive management of respiratory and cardiovascular function are essential. Admission to an intensive care unit is often required, and the focus on such supportive care has significantly improved mortality over the last 10 years.[10] A significant number of survivors are left with disabilities relating to limb amputation, skin damage, and neurological impairment.

PCR-based techniques have been of most importance in the fields of public health and epidemiology. The improved sensitivity of case ascertainment allows a more accurate measurement of the level of meningococcal disease in the human population, which is important for public health decision making.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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