Molecular Genetics Dm1

DM1 is caused by an unstable CTG expansion in the 3' untranslated region of the dystrophia myotonica protein kinase (DMPK) gene on chromosome 19q13.3 (Table 1).[1] Affected subjects are usually heterozygous for the expansion. Only six homozygous subjects have been reported.[2] In affected subjects the repeat length varies between 50 and 5000. Alleles with 50-80 repeats are

Table 1 Genetic differences/similarities between DM1/DM2

Genetic aspects

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Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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