Currently, multiplex PCR analyses that amplify deletion-prone exons are used as the first step for gene diagnosis. Two sets of PCR amplification are used to screen 19 deletion-prone exons (exons 1, 3, 4, 6, 8, 12, 13, 17, 19, 43-45, 47-52, and 60).[5,6] Using this method of examination, one finds that nearly half of the DMD cases are shown to have deletion mutations. Therefore, the rest of the cases need further examination to identify the responsible mutation in the dystrophin gene.
Was this article helpful?
The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.