Nat Polymorphism

An international committee has been established to oversee the nomenclature of the NATs[2] and a Web site that provides information about the naming of existing and new alleles for all species can be found at http:// www.louisville.edu/medschool/pharmacology/NAT.html.

Human NAT1 and NAT2 both have an approximate molecular mass of 33 kDa and each consists of 290 amino acids, sharing an 81% homology. NAT1 appears to be ubiquitously expressed, whereas NAT2 expression is restricted to the liver and gut. The active site of NAT enzymes contains the catalytic triad cysteine-histidine-aspartate,[1] which is similar to that of the cysteine protease superfamily of proteins.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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