Oncofetal Fibronectin

Oncofetal fibronectin has been proposed as a possible tool for the preoperative diagnosis of thyroid carcinomas, based on the finding that the expression of oncofetal fibronectin mRNA was significantly increased in papillary and anaplastic carcinomas, compared to normal thyroid tissues and follicular adenomas. Several reports using oncofetal fibronectin as a marker of malignancy showed that combined examination using both RT-PCR-based and cytological approaches may contribute to a more precise preoperative diagnosis of papillary and anaplastic carci-nomas.[3] However, other groups found that oncofetal fibronectin overexpression detected by immunohistology, but not RT-PCR, may yield an additional marker of papillary and anaplastic carcinomas.[4] Taken together, this particular marker is unlikely to benefit patients with ''follicular neoplasms'' and most of papillary lesion, although it may be helpful in diagnosing patients with papillary lesion and limited cellularity.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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