Other Dodsponsored Threat Agent Detection Platforms

In 2004, another real-time, handheld nucleic acid-based detection platform will become available for use by U.S. government agencies: the Razor, manufactured by Idaho

Fig. 3 The Idaho Technology, Inc., Razor instrument is an 8-lb. (3.6 kg) handheld real-time thermal cycler that performs the reactions in specially formatted plastic pouches (foreground) that contain freeze-dried reagents for up to 12 samples. The reagents are reconstituted via injection of sterile water through syringe ports on either end of the pouch. Inset: results of an assay are displayed to the user as plus/minus scoring on an LCD display panel. (Photo: James Higgins; inset: Matt Scullion, Idaho Technology, Inc., Salt Lake City, UT.) (View this art in color at www.dekker.com.)

Fig. 3 The Idaho Technology, Inc., Razor instrument is an 8-lb. (3.6 kg) handheld real-time thermal cycler that performs the reactions in specially formatted plastic pouches (foreground) that contain freeze-dried reagents for up to 12 samples. The reagents are reconstituted via injection of sterile water through syringe ports on either end of the pouch. Inset: results of an assay are displayed to the user as plus/minus scoring on an LCD display panel. (Photo: James Higgins; inset: Matt Scullion, Idaho Technology, Inc., Salt Lake City, UT.) (View this art in color at www.dekker.com.)

Technology, Inc. (Salt Lake City, UT; Fig. 3). The Razor builds on the experience of Idaho Technology's suitcase thermal cycler, the Ruggedized Advanced Pathogen Identification System (RAPID), which was designed in collaboration with personnel from the U.S. Air Force. The RAPID is essentially a ''combat'' version of the LightCycler® (which is licensed by Roche, Inc., for sale to non-U.S.-government laboratories) and has been used extensively for the detection of threat agents in the United States, Europe, and the Middle East. The RAPID is capable of using prepackaged, freeze-dried real-time PCR and RT-PCR reagents, and this convenience has been carried over to the Razor, in which reactions are performed in plastic pouches containing the freeze-dried reagents of interest. The end-user simply uses a conventional syringe to inject sterile water into the pouch, reconstitutes the reagents, injects template, and proceeds with the assay; up to 12 reactions can be done in one pouch. The Razor, which weighs 8 lb (3.6 kg) and can analyze the entire 12-sample pouch in approximately 22 min, is designed for field use off a battery power source. The instrument's software is preloaded with thermal cycling protocols for detection of a variety of threat agents, and results are presented to the user either via plus/minus scoring on the integral LCD display (Fig. 3), or via a more comprehensive graphical display on an attached laptop computer.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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