Phenotypegenotype Correlations

The different PWS molecular subtypes have very similar phenotypes with only minor differences noted by some studies. Patients with UPD tend to lack facial dys-morphisms, and African-American PWS patients often are of normal height and do not have small hands.[16] One recently reported important phenotype-genotype correlation is the higher prevalence of psychotic disorders among the patients with UPD compared to the other PWS types.[17] The molecular basis of this finding is currently unclear.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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