References

1. Alzheimer, A. Uber eine eigenartige Erkrangkung der Hirnrinde. Allg. Z. Psychiatr. Psych.-Gerichtl. Med. 1907, 64, 146-148.

2. Lennox, A.; Karlinsky, H.; Meschino, W.; Buchanan, J.A.; Percy, M.E.; Berg, J.M. Molecular genetics predictive testing for Alzheimer's disease: Deliberations and preliminary recommendations. Alzheimer Dis. Relat. Disord. 1994, 8, 126-147.

3. Lendon, C.L.; Ashall, F.; Goate, A.M. Exploring the etiology of Alzheimer disease using molecular genetics. J. Am. Med. Assoc. 1997, 277, 825-831.

4. Campion, D.; Dumanchin, C.; Hannequin, D.; Dubois, B.; Belliard, S.; Puel, M.; Thomas-Anterion, C.; Michon, A.; Martin, C.; Charbonnier, F.; Raux, G.; Camuzat, A.; Penet, C.; Mesnage, V.; Martinez, M.; Clerget-Darpoux, F.; Brice,

A.; Frebourg, T. Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum. Am. J. Hum. Genet. 1999, 65, 664670.

5. Risse, S.C.; Lampe, T.H.; Bird, T.D.; Nochlin, D.; Sumi, S.M.; Keenan, T.; Cubberley, L.; Peskind, E.; Raskind, M.A. Myoclonus, seizures, and paratonia in Alzheimer disease. Alzheimer Dis. Assoc. Disord. 1990, 4, 217 -225.

6. Cummings, J.L.; Vinters, H.V.; Cole, G.M.; Khachaturian, Z. Alzheimer's disease: Aetiologies, pathophysiology, cognitive reserve and treatment opportunities. Neurology 1998, 51 (Suppl. 1), S2-S17.

7. McKhann, G.; Drachman, D.; Folstein, M.; Katzman, R.; Price, D.; Stadlan, E.M. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34, 939-944.

8. Mirra, S.S.; Heyman, A.; McKeel, D.; Sumi, S.M.; Crain,

B.J.; Brownlee, L.M.; Vogel, F.S.; Hughes, J.P.; van Belle, G.; Berg, L.; Participating CERAD Neuropathologists The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part II. Standardization of the neuro-pathologic assessment of Alzheimer's disease. Neurology

9. Van Broeckhoven, C.L. Molecular genetics of Alzheimer disease: Identification of genes and gene mutations. Eur. Neurol. 1995, 35, 8-19.

10. Schellenberg, G.D.; Bird, T.D.; Wijsman, E.M.; Orr, H.T. Anderson, L.; Nemens, E.; White, J.A.; Bonnycastle, L. Weber, J.L.; Alonso, M.E.; Potter, H.; Heston, L.L. Martin, G.M. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science

11. Sherrington, R.; Rogaev, E.I.; Liang, Y.; Rogaeva, E.A.; Levesque, G.; Ikeda, M.; Chi, H.; Lin, C.; Li, G.; Holman, K.; Tsuda, T.; Mar, L.; Foncin, J.-F.; Bruni, A.C.; Montesi, M.P.; Sorbi, S.; Rainero, I.; Pinessi, L.; Nee, L.; Chumakov, I.; Pollen, D.; Brookes, A.; Sanseau, P.; Polinsky, R.J.; Wasco, W.; Da Silva, H.A.; Haines, J.L.; Pericak-Vance, M.A.; Tanzi, R.E.; Roses, A.D.; Frase,

P.E.; Rommens, J.M.; St George-Hyslop, P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 1995, 375, 754-760.

12. Levy-Lahad, E.; Wasco, W.; Poorkaj, P.; Romano, D.M.; Oshima, J.; Pettingell, W.H.; Yu, C.E.; Jondro, P.D.; Schmidt, S.D.; Wang, K.; Crowley, A.C.; Fu, Y.-H.; Guenette, Sy.; Galas, D.; Nemens, E.; Wijsman, E.M.; Bird, T.D.; Schellenberg, G.D.; Tanzi, R.E. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995, 269, 973-977.

13. Scheuner, D.; Eckman, C.; Jensen, M.; Song, X.; Citron, M.; Suzuki, N.; Bird, T.D.; Hardy, J.; Hutton, M.; Kukull, W.; Larson, E.; Levy-Lahad, E.; Vitanen, M.; Peskind, E.; Poorkaj, P.; Schellenberg, G.; Tanzi, R.; Wasco, W.; Lannfelt, L.; Selkoe, D.; Younkin, S. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the Presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 1996, 2, 864-870.

14. St George-Hyslop, P.H.; Tanzi, R.E.; Polinsky, P.J.; Haines, J.L.; Nee, L.; Watkins, P.C.; Myers, R.H.; Feldman, R.G.; Pollen, D.; Drachman, D.; Growdon, J.; Bruni, A.; Fonein, J.; Salmon, D.; Frommelt, P.; Amaducci, L.; Sorbi, S.; Piacentini, S.; Steward, G.D.; Hobbs, W.J.; Conneally, P.M.; Gusella, J.F. The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 1987, 235, 885-890.

15. Mann, D.M.; Esiri, M. The pattern of acquisition of plaques and tangles in the brain of patients under 50 years of age with Down syndrome. J. Neurol. Sci. 1989, 89, 169-179.

16. De Strooper, B.; Saftig, P.; Craessaerts, K.; Vandersti-chele, H.; Guhde, G.; Annaert, W.; VonFigura, K.; Van Leuven, F. Deficiency of Presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 1998, 391 (6665), 387-390.

17. Bertoli, A.; Marcheco, B.; Llibre, J.; Gomez, N.; Borrajero, I.; Severijnen, EA.; Joosse, M.; Van Duijin, C.M.; Heredero, L.; Heutink, P. A novel Presenilin 1 mutation (L174M) in a large Cuban family with early onset Alzheimer's disease. Neurogenetics 2002, 4, 97-104.

18. Sherrington, R.; Froelich, S.; Sorbi, S.; Campion, D.; Chi, H.; Rogaeva, E.; Levesque, G.; Rogaev, E.; Lin, C.; Liang, Y.; Ikeda, M.; Mar, L.; Brice, A.; Agid, Y.; Percy, M.; Clerget-Darpoux, F.; Piacentini, S.; Marcon, G.; Nacmias, B.; Amaducci, L.; Frebourg, T.; Lannfelt, L.; Rommens, J.; St George-Hyslop, P. Alzheimer's disease associated with mutations in Presenilin 2 is rare and variable penetrant. Hum. Mol. Genet. 1996, 5, 985-988.

19. Rogaev, E.I.; Sherrington, R.; Rogaeva, E.A.; Levesque, G.; Ikeda, M.; Liang, Y.; Chi, H.; Lin, C.; Holman, K.; Tsuda, T.; Mar, L.; Sorbi, S.; Naemisa, B.; Piacentini, S.; Amaducci, L.; Chumakov, L.; Cohen, D.; Lannfelt, L.; Fraser, P.E.; Rommens, J.M.; St George-Hyslop, P.H. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995, 376, 775778.

20. Janssen, J.C.; Beck, J.A.; Campbell, T.A.; Dickinson, A.; Fox, N.C.; Harvey, R.J.; Houlden, H.; Rossor, M.N.; Collinge, J. Early onset familial Alzheimer's disease: Mutation frequency in 31 families. Neurology 2003, 60, 235-239.

21. McConnell, L.M.; Koening, B.A.; Greely, H.T.; Raffin, T.A.; Alzheimer Disease Working Group of the Stanford Program in Genomics, Ethics, and Society. Genetic testing and Alzheimer disease: Has the time come? Nat. Med. 1998, 4, 757-759.

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