References

1. Gomez, M.; Sampson, J.; Whittemore, V. The Tuberous Sclerosis Complex; Oxford University Press: Oxford, England, 1999.

2. Curatolo, P. Tuberous Sclerosis Complex: From Basic Science to Clinical Phenotypes; MacKeith Press: Cambridge, England, 2003.

3. Cheadle, J.P.; Reeve, M.P.; Sampson, J.R.; Kwiatkowski, D.J. Molecular genetic advances in tuberous sclerosis. Hum. Genet. 2000, 107 (2), 97-114.

4. Dabora, S.L.; Jozwiak, S.; Franz, D.N.; Roberts, P.S.; Nieto, A.; Chung, J.; Choy, Y.S.; Reeve, M.P.; Thiele, E.; Egelhoff, J.C.; Kasprzyk-Obara, J.; Domanska-Pakiela, D.; Kwiatkowski, D.J. Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs. Am. J. Hum. Genet. 2001, 68 (1), 64-80.

5. Jones, A.C.; Shyamsundar, M.M.; Thomas, M.W.; May-nard, J.; Idziaszczyk, S.; Tomkins, S.; Sampson, J.R.; Cheadle, J.P. Comprehensive mutation analysis of TSC1 and TSC2—And phenotypic correlations in 150 families with tuberous sclerosis. Am. J. Hum. Genet. 1999, 64 (5), 1305-1315.

6. Roach, E.S.; Gomez, M.R.; Northrup, H. Tuberous sclerosis complex consensus conference: Revised clinical diagnostic criteria. J. Child Neurol. 1998, 13 (12), 624-628.

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8. Kwiatkowski, D.J. Rhebbing up mTOR: New insights on TSC1 and TSC2 and the pathogenesis of tuberous sclerosis. Cancer Biol. Ther. 2003, 2 (5), 471-476.

9. Lamb, R.F.; Roy, C.; Diefenbach, T.J.; Vinters, H.V.; Johnson, M.W.; Jay, D.G.; Hall, A. The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Nat. Cell Biol. 2000, 2 (5), 281 -287.

10. Kleymenova, E.; Ibraghimov-Beskrovnaya, O.; Kugoh, H.; Everitt, J.; Xu, H.; Kiguchi, K.; Landes, G.; Harris, P.; Walker, C. Tuberin-dependent membrane localization of polycystin-1: A functional link between polycystic kidney disease and the TSC2 tumor suppressor gene. Mol. Cell 2001, 7 (4), 823-832.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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