Ease of use, flexibility, and scalability are some of the advantages that make the Invader platform ideally suited for automation. Assays are readily adaptable from manual to semiautomated to fully automated ultra-high-throughput settings using a variety of standard plate formats. Most automated liquid handling systems can handle the assay setup, which requires only a few pipetting steps. Regardless of format, e.g., 96 or 384 wells, or setup, e.g., manual or automated, the robustness of the platform remains constant.[3]

The Invader platform—a highly accurate, cost-effective, and specific method for the detection of specific nucleic acid sequences—has been applied to the detection of thousands of SNPs in genome-wide association studies.[8,9] Simple, fast, reliable, and inexpensive diagnostic tools are essential not only for research purposes, but for clinical settings as well. Several analyte-specific reagents (ASRs) have been developed for use in clinical diagnostics, including Factor V Leiden (FVL), apolipo-protein E (ApoE), and cystic fibrosis (CFTR) mutation detection. The current clinical applications of the Invader platform include detection of coagulopathies and inherited diseases.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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