excessive release of inflammatory cytokines triggered by
the superantigens in host's organism.1'' Indeed, specific human leukocyte antigen class II haplotypes conferred strong protection from systemic diseases. Patients with the DRB1*1501/DQB1*0602 haplotype 9 mounted significantly reduced responses and were less likely to develop severe systemic diseases.171 This finding is supported by recent report showing that erythrogenic toxin SPE A binding to class II HLA is dependent on DQ a-chain polymorphisms such that HLA-DQA1*01 a-chains show greater binding than DQA1*03/05 a-chains.[241 10.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.