Sensitivity Requirements and Clinical Samples

Clinical applications of protein microarray technology require systems that: 1) are capable of detecting a broad dynamic range of analyte concentrations; 2) exhibit adequate sensitivity (in the femtomolar range) and specificity for detecting low abundance proteins; and 3) are capable of limiting interference from contaminating biologically active molecules such as peroxidases, biotin, avidin, and immunoglobulins.

Protein microarray technology may be directly applied to biopsies, tissue cell aspirates, or body fluid sam-ples.[1,27,28] The total number of cells required for microarray construction is dependent on the number of analyte molecules, the sensitivity of the detection system, and the number of analyte molecules/mole.[6]

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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