T Pallidum

T. pallidum causes venereal syphilis, also called ''the great imitator'' because the clinical features are similar to those of many other diseases. Untreated, syphilis progresses through several distinct stages. Following exposure and an incubation of 9 to 90 days, the primary stage becomes apparent and is characterized by a painless skin lesion called a chancre, and sometimes by regional lymphadenopathy. It is believed that T. pallidum is disseminated through the bloodstream within hours after initial contact with an infected person.[1-3] Chancres, which contain millions of organisms, usually heal spontaneously.1-3-1 The secondary stage of the disease is characterized by generalized mucocutaneous lesions and lymphadenopathy. This stage is followed by a latent pe

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riod, during which the infection can be detected only by serological tests. If the infection is left untreated, approximately one third of infected individuals will develop tertiary syphilis, characterized by gummatous lesions of any organ of the body including the cardiovascular or the nervous systems. Infants born to mothers infected with T. pallidum may contract congenital syphilis as a result of transplacental transmission. Congenital syphilis can be classified into distinct stages similar to those of acquired syphilis.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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