The TaqMan technology is also based on fluorescent probes. This technique takes advantage of the 5' nuclease activity of Taq polymerase. TaqMan probes have a reporter dye at the 5' end and a quencher dye at the 3' end. The close proximity of the two dyes in the intact probe quenches the fluorescent signal. However, during primer extension, Taq polymerase specifically displaces the annealed probe and allows the 5'-nuclease activity to cleave the probe and release the fluorescent dye. Light is
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.