The Aat Gene

The 12-kb gene is located on the long arm of chromosome 14 in a cluster of other serpins, and two major promoters have been identified: one for hepatocytes,[3] the cell type accounting for most of the circulating AAT, and the other, which is effective in other tissues such as monocytes and lung alveolar epithelial cells.[4] The gene is made up of four coding exons and three noncoding exons, and, during mRNA expression, the noncoding exons are differentially spliced. A diagrammatic representation of the gene is shown in Fig. 3.

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Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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