The Genome

Early studies analyzed the relationship between Y. pestis, Y. pseudotuberculosis, and Y. enterocolitica as well as other enteric gram-negative organisms at the whole-cell DNA hybridization level.[6] More recent experiments using multilocus sequence typing and IS100-based fingerprinting have clearly shown that Y. pestis is a recently emerged clone of Y. pseudotuberculosis with remarkably little sequence variability.[7] Y. pestis itself is extremely monomorphic at the DNA sequence level.

Two complete genomes from two biotypes of Y. pestis have been completed. The first was the modern biotype Orientalis strain CO92[2] and the second was the Medievalis strain KIM.[3] CO92 is a recent pneumonic plague isolate that is highly virulent, while KIM is a

Table 2 Interesting characteristics of complete sequences Y. pestis strains CO92 and KIMa
Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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