Tissue Arrays For Validation Of Biomarkers Identified Using Microarrays

Genomic analysis tools for biomarker identification can be complimented by the use of array-based high-throughput approaches to survey tumor biopsies for a large number of individual patients. In combination with the associated clinical data for these patients, this technology is ideally suited to a genomics- or proteo-mics-based discovery project and has the ability to significantly accelerate the transition of basic science findings into clinical applications (Fig. 2). The application of tissue microarrays represents a high-throughput approach for validation of potential novel markers for bladder cancer by immunohistochemistry or fluorescence in situ hybridization in paraffin blocks. Focus is intensified within this field to automate construction of tissue microarrays and generate arrays from frozen blocks.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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