Ube3a Deficiency

The UBE3A gene encodes E6-AP ubiquitin protein ligase, a protein that takes part of the ubiquitin-proteasome

Table 1 Molecular types of AS

Type

Mechanism

Laboratory testing

Proportion of all (%)

Recurrence risk

Phenotype

la

De novo

MTa+

70%

<1%

Severe

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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