The applications reviewed previously were all related to rapid and accurate identification of blood culture bottles with yeast or gram-positive bacteria; however, PNA probes for important gram-negative bloodstream pathogens, such as Escherichia coli and Pseudomonas aeruginosa, have also been described and are obvious candidates for an almost complete test panel for blood culture identification. The PNA-FISH platform has also been studied in several other applications, such as Mycobacterium tuberculosis in acid-fast bacilli (AFB)-positive sputum samples, cultures, and biopsies, and Trypanosome brucei in blood smears, with the latter being the first PNA-FISH application on parasites and yet another example of the broad applicability of the PNA-FISH platform.
Therefore, PNA-FISH offers almost unlimited opportunities for novel diagnostic applications to not just replace existing tests, but also to offer attractive solutions to unmet diagnostic needs that potentially lead to better patient therapy and management.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.