Keratin Disorders / Eli Sprecher 693

Lamivudine Resistance-Associated Gene Mutations / Harald H. Kessler, Evelyn Stelzl, and Alexander C. Haushofer 700

Laser Capture Microdissection / Falko Fend 703

Legionella spp. / Nele Wellinghausen and Michael Steinert 708

Ligase Chain Reaction (LCR) and Ligase Detection Reaction (LDR) / JUrgen Fuchs and Maurizio Podda 713

LightUp® Probes / Mikael Leijon 718

Liposomal Nonviral Delivery Vehicles / Nancy Smyth Templeton 721

Listeria spp.: DNA Probes and Conventional PCR Assays / Philippe Gilot 726

Listeria spp.: Other DNA-Based Identification Procedures and DNA-Based

Typing Methods / Philippe Gilot 730

Long-Distance PCR / Philip Lewis White and Sam Hibbitts 735

Long QT Syndrome / Carlo Napolitano and Silvia G. Priori 740

Loop-Mediated Isothermal Amplification (LAMP) / Kentaro Nagamine and

Tsugunori Notomi 745

MALDI-MS Coupled with Capillary LC and CE / Robert T. Kennedy and

Kerstin Nolkrantz 750

MALDI-TOF Mass Spectrometry / Christian Jurinke 756

Marfan Syndrome and Related Fibrillinopathies / Gwenaëlle Collod-Beroud and Catherine Boileau 761

Mass Spectrometric Genotyping of Single Nucleotide Polymorphisms / Christian Jurinke and Dirk van den Boom 766

Mastocytosis—c-Kit Mutations / M. Mayerhofer, C. Sillaber, M. Fodinger, K. Sotlar,

Medullary Thyroid Carcinoma (MTC) and Multiple Endocrine Neoplasia Syndromes

Medulloblastoma—MYC Messenger RNA Expression / Michael A. Grotzer 780

Melanoma Biomarkers—Molecular Profiling and Its Clinical Implications /

Pia Vihinen and Veli-Matti Kahäri 785

Melanoma, Familial / Femke A. de Snoo and Nicholas K. Hayward 791

Metabonomics and Its Role in Disease Diagnosis / John C. Lindon, Jeremy K. Nicholson, and Elaine Holmes 797

Microarrays—Confocal Scanning / Arthur E. Dixon and Savvas Damaskinos 803

Microarrays—Detecting DNA Copy-Number Changes / Beatriz Carvalho,

Marjan Marije Weiss, Bauke Ylstra, and Gerrit A. Meijer 808

Microarrays—Electronic Microarrays / Elaine M. Weidenhammer and Jay Shaw 814

Fabricating Microarrays / Mary Jane Cunningham and Dat D. Dao 819

Microarrays—Standard Operating Procedures / Thorsten Forster and Peter Ghazal 824

Microduplication Syndromes—17p11.2 Duplications, Proximal 15 Duplications, and Cat Eye Syndrome / Heather E. McDermid 831

Microplate Array Diagonal Gel Electrophoresis for SNP and Microsatellite

Genotyping and for Mutation Scanning / Ian N. M. Day, Tom R. Gaunt,

Xiao-he Chen, and Rosalind H. Ganderton 836

Microsatellite Instability / Wolfgang Dietmaier and Arndt Hartmann 842

Molecular Beacons and Other Hairpin Probes / Natalia E. Broude 846

Mucopolysaccharidosis Types IIIA and IIIB / Clare E. Beesley 851

Multiplex Real-Time PCR / Maurice M. Exner 855

Murray Valley Encephalitis Virus / David W. Smith, Annette K. Broom, and

John S. Mackenzie 860

Mycobacteria, Atypical / Chand Wattal and Sangeeta Joshi 865

Mycobacterium leprae / Diana L. Williams and Thomas P. Gillis 870

Mycoplasma spp. and Ureaplasma spp. / Florian Daxboeck 876

Myelodysplastic Syndrome—Risk Class Analysis by Microarray /

Wolf-Karsten Hofmann 881

Myotonic Dystrophy / Josef Finsterer 885

Nanotechnology-Based Lab-on-a-Chip Devices / K. K. Jain 891

NEBcutter—A Program to Cleave DNA with Restriction Enzymes / Janos Posfai,

R. J. Roberts, and Tamas Vincze 896

Neisseria meningitidis / Martin J. Callaghan, Dominic F. Kelly, and Andrew J. Pollard 901

Nested PCR and Multiplex Nested PCR / David Tarrago-Asensio and Ana Avellon-Calvo 906

Neuroblastoma—Clinical Implications of Real-Time PCR / Jorg Dotsch,

Wolfgang Rascher, and Holger Christiansen 911

Neurofibromatosis Type 1 / Bruce R. Korf 915

Neuronal Ceroid Lipofuscinoses / Nanbert Zhong 919

Nipah Virus / Michael S. Bronze and Ronald A. Greenfield 925

NIST Reference Materials for Medical Testing / Catherine D. O'Connell and John P. Jakupciak 929

Nucleic Acid Sequence-Based Amplification (NASBA) and Transcription-Mediated

Amplification (TMA) / Margareta Ieven and Katherine Loens 933

Oligonucleotide Design for PCR Primers and Microarray Probes / N. Sergeev,

Onchocerca volvulus / Thomas R. Unnasch 943

Orthopoxviruses—Monkeypox, Cowpox, Vaccinia, Camelpox, Mousepox /

M. Sofi Ibrahim and James D. Mellott 947

Osteogenesis Imperfecta / Anna Gajko-Galicka 953

p53 Status of Tumors: Diagnostic, Prognostic, and Therapeutic Exploitation /

Apollonia Tullo, Anna Maria D'Erchia, and Elisabetta Sbisa 957

Padlock Probes / David Y. Zhang and Josephine Wu 962

Paraoxonase (PON1) Gene Polymorphisms / Lucio G. Costa and Clement E. Furlong 965

Parkinsonism, Autosomal Dominant / Dominic Thyagarajan 970

Parvovirus B19 / Timm C. Harder and Peter Rautenberg 976

Patent Aspects in Proteomics and Genomics / Hans Wilhelm Meyers 981

PCR and RT-PCR Analysis in Archival Postmortem Tissues / Serena Bonin,

Francesca Petrera, and Giorgio Stanta 985

PCR Chemiluminescent Immunoassay (PCR-CLEIA) / Aldo Roda, Mara Mirasoli,

Patrizia Pasini, Simona Venturoli, Monica Musiani, and Marialuisa Zerbini 989

Personalized Medicine / K. K. Jain 994

Peutz-Jeghers Syndrome / William M. Grady and Andrew M. Kaz 1000

Plasmodium spp.—Detection by Molecular Techniques / Gabriella A. Farcas and Kevin C. Kain 1006

Plasmodium spp.—Detection of Drug Resistance by Molecular Techniques /

Gabriella A. Farcas and Kevin C. Kain 1010

Platelet Antigen Genotyping / Evelyne Kretzschmar and Heiner Trobisch 1015

PML/RARA and RARA FISH in Follow-up of Acute Promyelocytic Leukemia /

Dong Soon Lee 1021

PNA-FISH—Application for Chromosomal Analysis and Other Forms of

Genetic Testing / Franck Pellestor 1026

PNA-FISH—Applications for Rapid Diagnosis of Bloodstream Infections /

Henrik Stender 1031

Pneumocystis jiroveci / Hans Henrik Larsen, Jannik Helweg-Larsen, and Bettina Lundgren 1036

Point-of-Care Testing (POCT)—Nucleic Acid-Based Testing in a Point-of-Care Setting /

Jürgen Fuchs and Maurizio Podda 1042

Polymer Nonviral Delivery Vehicles / Ernst Wagner 1047

Polymerase Chain Reaction (PCR) / Guido Krupp and Ulrich Spengler 1052

Prader-Willi Syndrome / Milen Velinov, Edmund C. Jenkins, and W. Ted Brown 1060

Preimplantation Genetic Diagnosis—An Overview / The-Hung Bui, Erik Iwarsson, and Helena Malmgren 1065

Preimplantation Genetic Diagnosis—Single-Cell DNA and FISH Analysis /

Anver Kuliev and Yury Verlinsky 1070

Prenatal Diagnosis of Fetal RhD Status by Molecular Analysis of Maternal Blood /

Jean-Marc Costa and Alexandra Benachi 1074

Prenatal Diagnosis Using Fetal Cells and Cell-Free Fetal DNA in Maternal Blood /

Sinuhe Hahn and Wolfgang Holzgreve 1079

Protein Microarrays / Lance A. Liotta and Virginia Espina 1083

Protein Truncation Test (PTT) / Sadanand Gite, Alex Garvin, and Kenneth Rothschild 1089

Pseudoxanthoma Elasticum / Franziska Ringpfeil and Jouni Uitto 1095

Pulsed Field Gel Electrophoresis (PFGE) / Fann Wu, Preeti Pancholi, and

Phyllis Della-Latta 1099

Pyrosequencing / Dong-chuan Guo and Dianna M. Milewicz 1104

Quality of In-House Made High-Density Microarrays / Paul van den IJssel, Paul Eijk,

Erik Hopmans, Soemini Kasanmoentalib, and Bauke Ylstra 1108

Ramification Amplification / David Y. Zhang, Josephine Wu, Wandi Zhang, and Fei Ye 1113

Real-Time PCR / Stephen A. Bustin 1117

Real-Time PCR Platforms / Mikael Kubista and Neven Zoric 1126

Real-Time Reverse Transcription PCR / Stephen A. Bustin 1131

Restriction Fragment Length Polymorphism (RFLP)—Application for

Mycobacteria Typing / Karim Chemlal, Isdore Chola Shamputa, Nabil El AiLa,

Leen Rigouts, and Françoise Portaels 1136

Retinoblastoma / Dietmar Lohmann 1142

Retinoschisis, Juvenile (X-Linked) / Maria A. Musarella, Ian M. MacDonald, and Paul A. Sieving 1147

Retroviral Vectors / Erin L. Weber and Paula M. Cannon 1151

Reversed Line Blot Hybridization / Bert Gold 1157

Rh Genotyping—Clinical Aspects / Carlos M. Cotorruelo, Claudia Biondi, and Amelia Racca 1163

Ribotyping / Tim J. Inglis 1168

RNA Storage / Martin Hofmann 1172

Rolling-Circle Amplification (RCA) / Vadim V. Demidov 1175

Rotavirus / C. Anthony Hart and N. A. Cunliffe 1180

Salmonella spp. / Kenji Hirose, Ken-ichiro Itoh, and Haruo Watanabe 1186

Serial Analysis of Gene Expression (SAGE) Technology / Farid E. Ahmed 1191

Single Cell Gel Electrophoresis Assay (Comet Assay) / Lisa Giovannelli and

Vanessa Pitozzi 1197

Single Nucleotide Polymorphism (SNP) Genotyping Techniques—An Overview /

Richard M. Twyman 1202

Single-Tube Two-Round Real-Time PCR / Jorg Berg 1208

SNP Genotyping Using Single Molecule Fluorescence / Rudolf Franz Zirwes and Stephanie Bousart 1213

Spinal Muscular Atrophy / Shuji Ogino 1220

Staphylococcus aureus—Detection of MRSA / Sameer Elsayed 1225

Staphylococcus aureus—Toxin Detection / Karsten Becker 1230

Streptococcus pneumoniae / David R. Murdoch 1236

Streptococcus, Group A / Joseph E. Alouf and Heide Müller-Alouf 1241

Subtelomeric Rearrangements in Unexplained Mental Retardation /

Samantha J. L. Knight 1246

TaqMan Oligoprobes / Dino A. De Angelis 1253

Temporal Temperature Gradient Gel Electrophoresis / Lee-Jun C. Wong, Ozgul Alper,

Hae-Young Kwon, Duan-Jun Tan, and Tian-Jian Chen 1257

Tetracycline Resistance / Marilyn C. Roberts 1262

Thyroid Cancer—Detection of Tumor Cells by Molecular Methods / Jorg Bojunga and Stefan Zeuzem 1266

Tissue Microarrays in Pathology / Guido Sauter, Ronald Simon, and Martina Mirlacher 1271

Treponema pallidum, T. pertenue, T. endemicum, and T. carateum / Hsi Liu 1277

Trichinella spp. / Edoardo Pozio 1282

Trichomonas spp. / Holgar Mayta and Robert H. Gilman 1287

Tropheryma whipplei / R. Mahnel, T. Marth, F. Fenollar, and D. Raoult 1292

Trypanosoma cruzi / John M. Kelly, Martin C. Taylor, and Shane R. Wilkinson 1297

Tuberous Sclerosis / David J. Kwiatkowski 1302

Vibrio cholerae / Durg V. Singh 1307

Vibrio vulnificus / Olivier A. E. Sparagano and Brian Austin 1312

Viral Encephalitis—Japanese Encephalitis, Tick-Born Encephalitis, and

St. Louis Encephalitis / Matthias Niedrig and Jens Mehlhose 1316

Viral Hemorrhagic Fevers—Arenaviridae, Filoviridae, Bunyaviridae, and Flaviviridae /

Christian Drosten 1322

von Hippel-Lindau Disease / Deborah J. Marsh and Diana E. Benn 1329

Von Willebrand Disease / M. Said Enayat 1334

Wilson Disease / Juliane Halangk, Hartmut Schmidt, and Heiko Witt 1340

Wolff-Parkinson-White Syndrome, Familial / Robert Roberts 1345

Wuchereria bancrofti / Kosum Chansiri, Pornpimon Kanjanavas, Phaisan Khawsak,

Sintawee Khuchareontaworn, Sirichai Phantana, and Peerapan Tan-ariya 1349

Yersinia spp. / Luther E. Lindler 1355


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Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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