If a result of research in proteomics or genomics shall be licensed, in general a license agreement is concluded. The subject of a license agreement can be know-how or subject matter of an Intellectual Property Right (IPR), in most cases a patent or patent application. Therefore, it is recommended to file a patent application before starting negotiations.
Typically, targets, substances having physiological effects, methods, and technologies, can be subjects of license agreements. Whereas substances having physiological effects are candidates for drug development, so that classical license agreements can be concluded, agreements concerning targets often contain the so-called ''reach-through'' clauses. In the classical case, a license is granted to the drug developing party, which in turn pays royalties and/or down-payments to the licensor. Royalties are based on turnover figures achieved by commercialization of the drug. Targets are research tools for discovering drugs interfering with the target. A particular license agreement can contain clauses obliging the licensee to pay a royalty amount based on turnover figures related to any drug discovered and developed by using the target.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.