A

Actin cables, 71-86 Actin filaments, 89-90 Aetinoplanie acid, 153 Active site farnesy [transferase, 50 structure of, 37-46 AK.T-2,215 a-a Barrel structure, 24 a Subunit, 23,25 structure of, 37—40

proline-rich domain, 39 sequence repeats, 39 Alternative prenylaiion 90-93, 259, 261,

262,264 Andrastins A-D, 153 Awicancer agents, 214 Antitumor activity, 62, 204, 207 Apo-FTase, 90

264, 266, 269 Attrition rate, 3 Autocrine growth factors, 95

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