Alzheimers Disease Theory In

1907, the German physician/neurologist Alois Alzheimer (1864-1915) first described the brain lesions associated with the degenerative brain disease, now called Alzheimer's disease, which is characterized by loss of memory and emotional/psychological instability, and is accompanied by postmortem evidence of amyloid "plaques" and neurofibrillary "tangles" (insoluble nerve fibers). Some theorists speculate that the amyloid plaques (insoluble beta-amyloid proteins) are responsible for the symp toms where the neurofibrillary tangles are primary and the amyloid plaques are secondary. Related to the disorder is a deficit of the neurotransmitter acetylcholine and, perhaps, is caused by mutations/defects in mitochondrial DNA, prion (an infectious, rogue particle of protein), or "chromosome-21" (a chromosome implicated in genetic defects). See also FORGETTING/MEMORY, THEORIES OF. REFERENCE

Aronson, M. K. (1988). Understanding Alzheimer's disease. New York: Scrib-ner's.

AMBIVALENCE THEORIES OF HUMOR. The ambivalence theories of humor generally are characterized by oscillation, conflict-mixture, and simultaneously experienced incompatible emotions and feelings. The concepts of ambivalence and incongruity overlap, often, in humor theories and possess common features. However, the incongruity theories tend to emphasize cognitive, ideas, and perceptions whereas the ambivalence theories emphasize feelings and emotions as central to the humor experience. See also DESCARTES' THEORY OF HUMOR AND LAUGHTER; HUMOR, THEORIES OF; INCONGRUITY AND INCONSISTENCY THEORIES OF HUMOR.

All About Alzheimers

All About Alzheimers

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