Generic and Proprietary Names of Some Common Psychotropic Drugs

This list of drugs is not intended to be entirely comprehensive and in most cases only the most frequently used proprietary names are given. For detailed coverage of the area the reader is referred to a local pharmacopoeia. Our best efforts to ensure accuracy have been made. The publisher bears no responsibility for inaccuracy. European (mainly Irish UK) trade name Concilium Madopar (with L-dopa) Artane Cogentin Akineton Lexotan Parlodel Elaril Endep Asendin Benzedrine Auralgan European (mainly...

Potential cardiotoxicity of antipsychotic drugs

Most antipsychotic drugs have effects on the heart as a consequence of their pharmacological actions. Recently, thioridazine has been subjected to a restricted indication notice and the atypical antipsychotic sertindole had its licence withdrawn because of concerns about its potential cardiotoxicity. It has been known since the 1960s that ECG abnormalities are relatively common in those patients on antipsychotics, occurring in approximately 25 of all cases. The most commonly reported changes...

Neurochemical changes associated with Alzheimers disease

Scan Extrapyramidal Tracts

The pathological lesions seen in the brain of those with AD are inevitably associated with dysfunctions of the neurotransmitter systems. Of these, deficits in the neocortical cholinergic system have been well established for over a decade but more recently changes in the concentrations of the neuropeptides somatostatin and corticotrophin releasing factor (CRF) have been added to the list. Deficits in the biogenic amines noradrenaline and serotonin have also been reported to occur but a...